Fig. 4.

Venn diagram showing overlap of proteins found in E₂-, ICI-182,780-, and 4-OHT-induced ERα complexes. Of 108 proteins identified, 25 proteins were found enriched at the ERE under E₂ treatment and 20 were enriched under 4-OHT treatment, whereas no significant enrichment could be observed under ICI-182,780 (ICI) treatment. Additionally, seven proteins were found in all eluates, including control sample (not shown here). A 2-fold enrichment cutoff was set to discriminate between the treatments.