. 2010 May 25;9(9):1954–1967. doi: 10.1074/mcp.M110.000554

Table II. Plasma proteins with differential relative concentrations at p value <0.05.

Accession numbers of all proteins in each PGC, corresponding genes (gene symbol) and protein names, p values calculated by the robust eBayes test, and fold-changes with directions (plus and minus signs for up- and down-regulated in BCAR-positive relative to -negative, respectively) are given. HMW, high molecular weight; LMW, low molecular weight.

PGC^b	Accession number	Gene symbol^b	Protein name	p value^b	Fold-change^b
111	IPI00759754.1	TTN	Isoform 1 of Titin	<0.001	+1.21^a
	IPI00749039.2	TTN	titin isoform N2-A
	IPI00179357.2	TTN	Isoform 7 of Titin
	IPI00023283.3	TTN	Isoform 2 of Titin
	IPI00759542.1	TTN	Isoform 8 of Titin
	IPI00759637.1	TTN	Isoform 4 of Titin
	IPI00759613.1	TTN	Isoform 5 of Titin
	IPI00375499.2	TTN	titin isoform novex-2
	IPI00375498.2	TTN	titin isoform novex-1
	IPI00455173.4	TTN	Isoform 3 of Titin
	IPI00412307.8	TTN	2268-kDa protein
	IPI00884109.1		Cellular titin isoform PEVK variant 3 (fragment)

18	IPI00789376.1	KNG1	KNG1 protein	0.001	−1.18^a
	IPI00797833.3	KNG1	Kininogen-1
	IPI00032328.2	KNG1	Isoform HMW of kininogen-1 precursor
	IPI00215894.1	KNG1	Isoform LMW of kininogen-1 precursor

108	IPI00032311.4	LBP	Lipopolysaccharide-binding protein precursor	0.006	+1.22^a

222	IPI00395488.2	VASN	Vasorin precursor	0.007	+1.14

23	IPI00019943.1	AFM	Afamin precursor	0.007	−1.29^a

224	IPI00873854.1	MSTP9	64-kDa protein	0.009	+1.09
	IPI00292218.4	MST1	Hepatocyte growth factor-like protein precursor
	IPI00384647.1	MST1	Hepatocyte growth factor-like protein homolog
	IPI00718805.1	MSTP9	Brain rescue factor-1
	IPI00847702.2	MST1	14-kDa protein

135	IPI00301143.5	PI16	Isoform 1 of peptidase inhibitor 16 precursor	0.013	+1.25^a
135	IPI00845506.1	PI16	Isoform 2 of peptidase inhibitor 16 precursor	0.013	+1.25^a

97	IPI00007221.1	SERPINA5	Plasma serine protease inhibitor precursor	0.019	−1.22^a

104	IPI00165972.3	CFD	Complement factor D preproprotein	0.020	+1.43^a

38	IPI00303963.1	C2	Complement C2 precursor (fragment)	0.019	+1.09
38	IPI00643506.3	C2	Complement component 2	0.019	+1.09

116	IPI00004373.1	MBL2	Mannose-binding protein C precursor	0.021	+1.37^a

125	IPI00007199.4	SERPINA10	Protein Z-dependent protease inhibitor precursor	0.023	+1.23^a

26	IPI00022395.1	C9	Complement component C9 precursor	0.029	+1.13

230	IPI00022331.1	LCAT	Phosphatidylcholine-sterol acyltransferase precursor	0.030	−1.18^a

103	IPI00868938.1		β₂-Microglobulin	0.032	+1.27^a
	IPI00796379.1	B2M	B2M protein
	IPI00004656.2	B2M	β₂-Microglobulin

69	IPI00219583.1	SHBG	Isoform 2 of sex hormone-binding globulin precursor	0.032	−1.19^a
69	IPI00023019.1	SHBG	Isoform 1 of sex hormone-binding globulin precursor	0.032	−1.19^a

29	IPI00749179.2	C1S	Uncharacterized protein C1S	0.040	+1.08
29	IPI00017696.1	C1S	Complement C1s subcomponent precursor	0.040	+1.08

100	IPI00296176.2	F9	Coagulation factor IX precursor	0.043	+1.09
100	IPI00816532.1	F9	Coagulation factor IX (fragment)	0.043	+1.09

^a PGCs with fold-change ≥1.15 included in the multivariate classifier.

^b The values of the measures in these columns correspond to the whole protein group code (PGC) and not to a particular protein identifier.