Table 5.
Mixed linear models for the dependant variable first-phase insulin secretion
| Estimate | s.e. | P | |
|---|---|---|---|
| First-phase insulin secretion (obese subjects only) | |||
| Intercept | –0.990 | 1.486 | 0.508 |
| S I | –0.281 | 0.105 | 0.010 |
| Total fat | 0.935 | 0.208 | <0.001 |
| AfADM | 0.005 | 0.002 | 0.062 |
| First-phase insulin secretion (lean subjects only) | |||
| Intercept | –1.378 | 1.624 | 0.419 |
| S I | 0.032 | 0.119 | 0.782 |
| Total fat | 0.344 | 0.141 | 0.145 |
| AfADM | 0.006 | 0.002 | 0.014 |
Models were conducted separately within the obese and lean subgroups. All models were adjusted for age, pubertal stage, age-nested-in-pubertal stage, and SES.
AfADM, African genetic admixture; SES, socioeconomic status; SI, insulin sensitivity index.