Table 3.
Gene Top 10
CBP T30 Versus T0 | p300 T30 Versus T0 | ||||
---|---|---|---|---|---|
Gene | P-value | Ratio | Gene | P-value | Ratio |
CATSPER3 | 0 | 2.58 | THBS1 | ![]() |
6.07 |
ATF3 | ![]() |
4.51 | ATF3 | ![]() |
5.83 |
TRIP13 | ![]() |
11.07 | FOSB | ![]() |
14.03 |
CYR61 | ![]() |
6.43 | CYR61 | ![]() |
6.33 |
FOSB | ![]() |
10.03 | EGR1 | ![]() |
14.11 |
SMAD3 | ![]() |
2.09 | TPM1 | ![]() |
4.81 |
TMEM49 | ![]() |
2.32 | DUSP1 | ![]() |
6.81 |
MYH9 | ![]() |
2.39 | MYH9 | ![]() |
2.84 |
CRISPLD2 | ![]() |
2.89 | NR4A1 | ![]() |
13.16 |
THBS1 | ![]() |
4.15 | CRISPLD2 | ![]() |
4.04 |
T0 p300 Versus CBP | T30 p300 Versus CBP | ||||
---|---|---|---|---|---|
Gene | P-value | Ratio | Gene | P-value | Ratio |
CXXC1 | ![]() |
22.71 | CXXC1 | ![]() |
20.32 |
AKT1S1 | ![]() |
6.03 | MKKS | ![]() |
3.87 |
FBXL19 | ![]() |
5.56 | CATSPER3 | ![]() |
1.44 |
MKKS | ![]() |
4.73 | AKT1S1 | ![]() |
4.46 |
C3orf19 | ![]() |
7.93 | FAM40A | ![]() |
4.21 |
BSCL2 | ![]() |
8.25 | FBXL19 | ![]() |
3.27 |
THBS1 | ![]() |
2.1 | ZNF350 | ![]() |
9.14 |
MADCAM1 | ![]() |
7.85 | METTL3 | ![]() |
13.47 |
ZNF175 | ![]() |
17.86 | MADCAM1 | ![]() |
7.2 |
C1orf174 | ![]() |
9.84 | C1orf174 | ![]() |
7.25 |
Top 10 genes that are most significantly different between time points and coactivators according to the P-values of the Fisher’s exact test. The ratio shows the quantitative difference in binding as expressed by the number of tags between the two samples that are compared: from T30 and T0 (upper half of the table) and from p300 and CBP (lower half of the table).