Table 1.
miRs regulated by HOXA9 in BM cells
| miRNA | Expression levels | Fold change | P-value |
|---|---|---|---|
| miRs down-regulated by HoxA9 | |||
| miR-15b | High | 0.77 ± 0.12 | 0.02 |
| miR-23a | High | 0.40 ± 0.06 | 0.01 |
| miR-25 | High | 0.55 ± 0.14 | 0.01 |
| miR-320 | High | 0.78 ± 0.02 | 0.01 |
| miR-342 | High | 0.48 ± 0.07 | 0.01 |
| miRs up-regulated by HoxA9 | |||
| miR-19b | High | 1.53 ± 0.10 | 0.001 |
| miR-106b | High | 1.43 ± 0.38 | 0.03 |
| miR-147 | High | 2.46 ± 0.93 | 0.03 |
| miR-155 | High | 1.56 ± 0.24 | 0.001 |
| miR-191 | High | 1.27 ± 0.18 | 0.014 |
| miR-297 | High | 2.21 ± 0.29 | 0.0002 |
| miR-122a | Medium–high | 2.67 ± 1.60 | 0.04 |
| miR-142-5p | Medium | 3.94 ± 2.30 | 0.05 |
| miR-302c-AS | Medium | 1.67 ± 0.34 | 0.003 |
| miR-124a-mm | Medium–low | 3.45 ± 2.60 | 0.05 |
| miR-142-3p | Medium–low | 3.98 ± 1.80 | 0.04 |
| miR-190 | Medium–low | 3.42 ± 0.11 | 0.01 |
| miR-211 | Medium–low | 3.50 ± 2.01 | 0.01 |
| miR-326 | Medium–low | 3.64 ± 2.10 | 0.03 |
| miR-525 | Medium–low | 5.07 ± 1.20 | 0.0002 |
| miR-34c | Low | 3.68 ± 1.51 | 0.01 |
| miR-98 | Low | 3.31 ± 1.21 | 0.02 |
| miR-181c | Low | 2.78 ± 1.23 | 0.03 |
| miR-200c | Low | 2.21 ± 0.62 | 0.02 |
| miR-301 | Low | 3.25 ± 1.88 | 0.04 |
| miR-383 | Low | 3.85 ± 1.63 | 0.04 |
| miR-422b-mm | Low | 2.24 ± 1.15 | 0.04 |
| miR-518b | Low | 4.64 ± 0.79 | 0.0002 |
| miR-524 | Low | 3.58 ± 1.14 | 0.0004 |
| miR-527 | Low | 3.29 ± 0.18 | 0.003 |
| miR-30e-3p | Very low | 3.81 ± 1.58 | 0.02 |
| miR-143 | Very low | 3.56 ± 2.04 | 0.01 |
| miR-204 | Very low | 4.13 ± 2.14 | 0.01 |
| miR-485-5p | Very low | 2.96 ± 1.25 | 0.05 |
| miR-518f | Very low | 4.98 ± 1.58 | 0.004 |
| Highly expressed miRs in BM, not regulated by HoxA9 | |||
| let-7a–7i | Very high | 0.99 ± 0.25 | 0.79 |
| miR-21 | Very high | 1.03 ± 0.13 | 0.67 |
| miR-93 | Very high | 0.97 ± 0.08 | 0.81 |
| miR-103 | Very high | 0.96 ± 0.45 | 0.71 |
| miR-106 | Very high | 0.96 ± 0.21 | 0.71 |
| miR-107 | Very high | 1.00 ± 0.24 | 0.90 |
| miR-210 | Very high | 1.04 ± 0.24 | 0.88 |
| miR-223 | Very high | 1.03 ± 0.22 | 0.90 |
| miR-494 | Very high | 1.00 ± 0.05 | 0.96 |
| miR-22 | High | 1.03 ± 0.25 | 0.85 |
| miR-23b | High | 0.97 ± 0.20 | 0.77 |
| miR-26a,b | High | 1.00 ± 0.28 | 0.95 |
| miR-29a | High | 1.01 ± 0.30 | 0.79 |
| miR-30a-5p | High | 1.04 ± 0.18 | 0.91 |
| miR-30c | High | 1.03 ± 0.38 | 0.92 |
| miR-31 | High | 1.01 ± 0.35 | 0.87 |
| miR-103b | High | 1.08 ± 0.28 | 0.75 |
| miR-181a | High | 1.06 ± 0.26 | 0.68 |
| miR-185 | High | 1.08 ± 0.34 | 0.79 |
| miR-198 | High | 0.96 ± 0.48 | 0.94 |
| miR-221 | High | 0.99 ± 0.10 | 0.88 |
| miR-513 | High | 1.00 ± 0.45 | 0.84 |