Table 2.

Phenotype quantification of cell size, filopodia number and number of projections in HeLa cells either over-expressing Larp1 (FLAG-Larp1), after treatment using transfection reagent alone, cells treated with Larp1 RNAi or control RNAi

	Control RNAi median (IQR) n = 192	Larp1 RNAi median (IQR) n = 178	P-value	FLAG Control median (IQR) n = 202	FLAG Larp1 median (IQR) n = 234	P-value
Filopodia	35 (23–53)	61 (43–75)	<0.001	40 (25–55)	35 (22–47)	0.04
Area	2000 (1440–2800)	2320 (1750–3444)	0.006	2400 (1600–3400)	1500 (1000–2275)	<0.001
Protrusions	0 (0–1)	0 (0–0)	0.005	0 (0–2)	2 (0–3)	<0.001
Filopodia / area	0.016 (0.011–0.029)	0.026 (0.015–0.038)	<0.001	0.018 (0.009–0.026)	0.023 (0.013–0.036)	0.001
Protrusions / area	0.000 (0.000–0.001)	0.000 (0.000–0.000)	0.004	0.001 (0.000–0.002)	0 (0–6)	<0.001

Data analysed using Mann–Whitney U test.