Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2010 May 5;38(16):5479–5492. doi: 10.1093/nar/gkq338

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2010. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 7. — Stop codon specificity of read-through in eRF1 N-domain mutants. The boxed panel shows as reference a summary of residues identified in previous studies. Cavities 1–3 refers to residues identified by Bertram et al. (4), pocket 1/2 to residues identified by Hatin et al. (6). The K and S residues of the TASNIKS motif, and the C124 residue identified by Fan-Minogue et al. (5), are also shown. The other three panels show the same view of the eRF1 N-domain, with residues mutated in this study shown in spacefill and colour coded according to the level of stop codon read-through observed. Residues of mutants conferring strong UGA-specific read-through are indicated.