Table 1.

Experimental knob A peptides and corresponding properties

Peptide sequence	Property	Net charge
GPRVVERC	Mimics native sequence through seventh residue	+1
GPRVVAAC	Mimics native sequence minus additional charged residues	+1
GPRPAAC	Stabilized backbone	+1
GPRPFPAC	Stabilized backbone	+1
GPRPPERC	Stabilized backbone and additional charged residues	+1
GPSPAAC	Negative control; known dysfibinrogen mutant	0