Table 2. Association between EGFR and mTOR pathways and clinical–pathological parameters (n=107).

	EGFR	p-ERK	p-AKT	p-mTOR	p-p70s6K	ChemoTx	pT-stage	pN-stage	DFS	OS
EGFR		P=0.02	NS	P=0.0001	NS	P=0.038	NS	NS	NS	NS
p-ERK	P=0.02		P=0.0001	NS	NS	NS	NS	NS	NS	NS
p-AKT	NS	P=0.0001		NS	NS	NS	NS	NS	NS	NS
p-mTOR	P=0.0001	NS	NS		P=0.001	NS	P=0.048	NS	NS	NS
p-p70s6K	NS	NS	NS	P=0.001		NS	P=0.02	P=0.001	NS	NS

Abbreviations: DFS=disease-free survival; EGFR=epidermal growth factor receptor; mTOR=mammalian target of rapamycin; NS=not significant; OS=overall survival; p-AKT=phosphorylated AKT; p-ERK=phosphorylated extracellular signal-regulated kinase.