Table 4. Sensitivity and specificity analysis of Mcm5 test performance in normal controls and prostate cancer patients.
| n | % (CI) | ||
|---|---|---|---|
| All cancer patients | |||
| Before massage | 83 | Sensitivity | 65 (54–75) |
| After massage | 60 | Sensitivity | 78 (66–88) |
| Highest Mcm5 signal | 88 | Sensitivity | 82 (72–89) |
| Cancer patients before and after massage | |||
| Before massage | 55 | Sensitivity | 60 (46–73) |
| After massage | 55 | Sensitivity | 82 (69–91)a |
| Normal controls | |||
| Strictly normal group – before massage | 28 | Specificity | 93 (76–99) |
| Expanded cohort – before massage | 331 | Specificity | 73 (68–78) |
Abbreviations: CI=confidence interval; Mcm=minichromosome maintenance.
a
Compared with before massage, P=0.012 (McNemar's test).
Sensitivity and specificity were determined using a cut point of 1800 for Mcm5 signal.