Table 1. Drug list for ATP-TCA with manufacturer and 100% TDC used in the assay and the number of tumours tested with each drug.
Drug or combination | Manufacturer | 100% TDC (μM) | Number tested |
---|---|---|---|
Cisplatin | Bristol-Myers-Squibba | 10.00 | 27 |
Doxorubicin | Eli Lillyb | 0.92 | 19 |
Gemcitabine | Eli Lilly | 40.04 | 26 |
Paclitaxel | Bristol-Myers-Squibb | 15.90 | 26 |
Topotecan | GlaxoSmithKlinec | 1.78 | 23 |
Treosulfan | Medacd | 71.86 | 23 |
Cisplatin+Gemcitabine | As single agents | As single agents | 27 |
Treosulfan+Gemcitabine | As single agents | As single agents | 26 |
Abbreviation: TDC=test drug concentration.
Some samples had too few cells for all single agents and combinations to be tested.
Bristol-Myers Squibb Pharmaceuticals Limited, Uxbridge, Middlesex, UK.
Eli Lilly and Company Limited, Basingstoke, Hampshire, UK.
GlaxoSmithKline plc, Brentford, Middlesex, UK.
medac GmbH, Hamburg, Germany.