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. 2010 Jul 27;103(5):649–655. doi: 10.1038/sj.bjc.6605819

Figure 2.

Figure 2

(A) Sensitive xenografts had focal gains in RAS, or homozygous deletions in PTEN or FHIT, potentially leading to pathway activation. Red colour represents gene copy number gains. Green colour represents gene copy number losses. (B) Tumour regression after treatment with temsirolimus in direct pancreatic cancer xenografts was correlated with baseline phospho-p70S6K. Green dots represent xenografts that experienced tumour regression after temsirolimus treatment. Red dots represent xenografts that experienced tumour growth.