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. 2010 Sep 7;6:387–392. doi: 10.2147/ndt.s11704

Figure 2.

Figure 2

The three phases of urinary response to amino acid dosing (Two urinary neurotransmitter tests are required to determine the phase with certainty). PHASE 1: In phase 1, as the amino acid dosing increases or decreases the urinary serotonin or dopamine decreases or increases respectively. In phase 1, there is inappropriate excretion of neurotransmitters into the urine instead of the system where they are needed. PHASE 2: In phase 2, as the amino acid dosing increases or decreases the urinary serotonin or dopamine is low (<80 μg/g creatinine for serotonin or <300 μg/g creatinine for dopamine). In phase 2, there is no inappropriate excretion of neurotransmitters into the urine. The neurotransmitters are being excreted appropriately into the system and the urine. PHASE 3: In phase 3, as the amino acid dosing increases or decreases the urinary serotonin or dopamine increases or decreases respectively. In phase 3, there are adequate systemic serotonin and dopamine levels. The excess serotonin and dopamine are appropriately excreted into the urine.