Figure 3.

Median percentage reduction in seizure frequency per 28 days from the baseline period to the maintenance period. Pooled efficacy data of SP667, SP754, and SP755 trials.

Notes: *P < 0.05, **P < 0.001 vs placebo. Inferential statistics for the 75% responders are not available. Copyright © 2009. Reproduced with permission from Beydoun A, D'Souza J, Hebert D, Doty P. Lacosamide: pharmacology, mechanisms of action and pooled efficacy and safety data in partial-onset seizures. Expert Rev Neurother. 2009;9(1):33–42.

Abbreviation: LCM, lacosamide.