Table 2. Body weight, blood glucose, triglycerides, total cholesterol, LDL and HDL in wt and ApoE−/− mice, fed normal chow or HFD (experimental set 2).
Genotype | Body weight (g) | Blood glucose (mmol/l) | Triglycerides (mmol/l) | Total cholesterol (mmol/l) | HDL cholesterol (mmol/l) | LDL cholesterol (mmol/l) |
wt chow diet (n = 7) | 24.0±4.9 | 9.3±2.9 | 0.63±0.41 | 1.76±0.48 | 0.71±0.23 | 0.76±0.35 |
ApoE−/− chow diet (n = 5) | 23.6±1.7 | 9.4±0.6 | 0.47±0.11 | 10.35±5.19 ** | 0.20±0.08 *** | 6.77±1.10 ** |
ApoE−/− HFD (n = 5) | 22.5±1.0 | 8.1±0.8 | 0.62±0.12 | 8.81±4.72 * | 0.27±0.12 ** | 13.11±5.48 *** # |
Values represent mean ± SD. HFD, high fat diet; HDL, high density lipoprotein; LDL, low density lipoprotein. HDL/LDL data are missing for one of the ApoE−/− animals fed with HFD, since the HDL value was below detection limit. One-way analyses of variance followed by Bonferroni tests were performed;
*p<0.05,
**p<0.01,
***p<0.001 vs. wt chow diet;
p<0.05 vs. ApoE−/− chow diet.