FIG. 7.

Intravascular (IV) and intramuscular (IM) pressure recording during HLV injection. In rhesus monkeys, intravenous pressure was measured through a catheter inserted into a vein adjacent to the injection catheter and intramuscular pressure was measured through a fluid-filled catheter inserted directly into a muscle. The tourniquet was applied to the leg just before the start of the data collection. “A” indicates when the injection catheter was flushed and the tourniquet was inflated to 450 mmHg. “B” indicates when the pDNA injection was started at a rate of 0.5 ml/min. “C” indicates the end of the pDNA injection. “D” indicates the point at which the tourniquet was deflated and removed from the limb.