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. 2010 Aug 10;5(8):e12097. doi: 10.1371/journal.pone.0012097

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Jamali et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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a) The perimeter of the cell and nucleus (i.e. their corresponding membranes) are initially discretized into nodes (points). The superscript indicates that the point is on the cell membrane and superscript represents a point on the nuclear membrane. If neither nor are specified, the given point can be assumed to lie on either the cell membrane or nucleus. For example, the membrane's point of cell represented by . Each line that connects two points (red, green and blue lines) refers to a Voigt subunit. The total force that acts on each point is and is calculated by Eq(1) b) Voigt subunit. A linear Kelvin-Voigt solid element, represented by a purely viscous element (a damper) and purely elastic element (a spring) connected in parallel. The force that is exerted on from this subunit is (Eq.(2)). is the spring constant and represents viscosity.

Inline graphic — a) The perimeter of the cell and nucleus (i.e. their corresponding membranes) are initially discretized into nodes (points). The superscript indicates that the point is on the cell membrane and superscript represents a point on the nuclear membrane. If neither nor are specified, the given point can be assumed to lie on either the cell membrane or nucleus. For example, the membrane's point of cell represented by . Each line that connects two points (red, green and blue lines) refers to a Voigt subunit. The total force that acts on each point is and is calculated by Eq(1) b) Voigt subunit. A linear Kelvin-Voigt solid element, represented by a purely viscous element (a damper) and purely elastic element (a spring) connected in parallel. The force that is exerted on from this subunit is (Eq.(2)). is the spring constant and represents viscosity.