| Model Parameter | Parameter Value | Cost-Effectiveness, $ per QALY | ||||
|---|---|---|---|---|---|---|
|
| ||||||
| Base case | Min value | Max value | Base case | Low CER | High CER | |
| Probability of reducing risk factors without an mDPP | 12.1% | 3.2% | 25.9% | 3,420 | 783 | 18,580 |
| Probability of enrollment in an mDPP | 47.0% | 9.2% | 86.7% | 3,420 | 1,911 | 16,707 |
| Probability of reducing risk factors with an mDPP | 16.2% | 4.2% | 34.4% | 3,420 | 0 | 13,087 |
| Probability of screening risk-factor–positive | 31.0% | 7.2% | 63.5% | 3,420 | 1,818 | 14,046 |
| Utility for risk-factor–positive patients with an mDPP | 0.75 | 0.73 | 0.77 | 3,420 | 1,926 | 13,178 |
| Probability of diabetes for risk-factor–positive patients without an mDPP | 10.8% | 2.9% | 23.3% | 3,420 | 0 | 8,505 |
| Probability of diabetes for risk-factor–positive patients with an mDPP | 4.8% | 1.3% | 10.5% | 3,420 | 1,911 | 7,085 |
| Utility for risk-factor–positive patients without an mDPP | 0.73 | 0.71 | 0.75 | 3,420 | 2,280 | 7,301 |
Abbreviations: QALY, quality-adjusted life-year; Min, minimum; Max, maximum; CER, cost-effectiveness ratios; mDPP, modified Diabetes Prevention Program.