Table 5.
Toxicity | No. (%) with grades 3-4 toxicity |
---|---|
Non Hematologic toxicities | |
Bone or Joint aches | 11 (26) |
Others(a) | 10 (24) |
Skins rash | 3 (7) |
Nausea | 2 (5) |
Diarrhea | 2 (5) |
Muscle cramps | 2 (5) |
Hematologic toxicities | |
Granulocytopenia < 1·109/liter | 14 (33) |
Thrombocytopenia <50·109/liter | 10 (24) |
Anemia < 8 g/d liter | 5 (12) |
(a)2 with fever, 1 with neurological depression symptoms, and 1 with cardiac symptoms, fatigue 6.