Table 3.

Regression analysis results.

Time of measurement	MRI variable	Regression coefficient	p value	R2
Baseline	NBV	0.304	0.802	0.004
	Gd+ lesion number	−0.108	0.144	0.018
	Gd+ lesion volume	−0.028	0.252	0.013
	T2 lesion number	−0.175	0.024	0.042
	T2 lesion volume	−0.108	0.069	0.028
On-study	Gd+ lesion number	−0.073	0.160	0.016
	Gd+ lesion volume	−0.044	0.044	0.033
	T2 lesion number	−0.003	0.220	0.013
	T2 lesion volume	−0.112	0.060	0.028
	PBH	−0.064	0.003	0.067

Results of univariate multiple linear regression analysis for the relation between PBVC and predictive/explanatory MRI variables. All models were corrected for age, sex, and disease duration

NBV normalized brain volume, Gd+ gadolinium-enhancing, PBH persistent black hole