Table 2.
Comparison of imaging parameters for patients with CKD and with and without fractures
| Parameter | Fracture (mean ± SD) | No Fracture (mean ± SD) | % Difference | OR (95% CI) | AUC (95% CI) |
|---|---|---|---|---|---|
| DXA | |||||
| total LS BMD (g/cm2) | 0.957 ± 0.173 | 1.069 ± 0.203a | −10 | 1.93 (1.15 to 3.25) | 0.66 (0.54 to 0.78) |
| total LS T score | −1.1 ± 1.5 | −0.1 ± 1.8a | 1.91 (1.15 to 3.17) | 0.67 (0.55 to 0.78) | |
| TH BMD (g/cm2) | 0.840 ± 0.171 | 0.923 ± 0.176b | −9 | 1.65 (1.02 to 2.67) | 0.63 (0.50 to 0.75) |
| TH T score | −1.2 ± 1.1 | −0.7 ± 1.1 | 1.60 (0.98 to 2.58) | 0.61 (0.49 to 0.73) | |
| FN BMD (g/cm2) | 0.677 ± 0.127 | 0.755 ± 0.154b | −10 | 1.86 (1.10 to 3.14) | 0.66 (0.55 to 0.78) |
| FN T score | −1.9 ± 0.9 | −1.4 ± 1.1b | 1.76 (1.05 to 2.99) | 0.62 (0.50 to 0.75) | |
| 1/3R BMD (g/cm2) | 0.652 ± 0.107 | 0.697 ± 0.117 | −7 | 1.51 (0.96 to 2.37) | 0.60 (0.48 to 0.72) |
| 1/3R T score | −1.6 ± 1.8 | −1.2 ± 1.4 | 1.30 (0.84 to 2.02) | 0.52 (0.39 to 0.65) | |
| UDR BMD (g/cm2) | 0.363 ± 0.084 | 0.430 ± 0.093a | −16 | 2.29 (1.34 to 3.89) | 0.68 (0.57 to 0.80) |
| UDR T score | −2.1 ± 1.4 | −1.3 ± 1.2c | 1.94 (1.17 to 3.21) | 0.62 (0.50 to 0.75) | |
| HRpQCT, radius | |||||
| total area (mm2) | 274 ± 59 | 293 ± 73 | −6 | 1.33 (0.85 to 2.08) | 0.56 (0.44 to 0.69) |
| CtArea (mm2) | 45 ± 15 | 55 ± 19a | −18 | 1.85 (1.12 to 3.08) | 0.63 (0.51 to 0.75) |
| trabecular area (mm2) | 228 ± 53 | 237 ± 69 | −4 | 1.15 (0.74 to 1.79) | 0.52 (0.40 to 0.65) |
| Dtot (mg HA/cm3) | 255 ± 63 | 300 ± 71a | −15 | 2.11 (1.24 to 3.57) | 0.66 (0.54 to 0.77) |
| Dcort (mg HA/cm3) | 801 ± 82 | 825 ± 81 | −3 | 1.35 (0.87 to 2.10) | 0.56 (0.43 to 0.68) |
| Dtrab (mg HA/cm3) | 122 ± 43 | 151 ± 48a | −19 | 2.01 (1.21 to 3.34) | 0.65 (0.53 to 0.77) |
| BV/TV (%) | 10.2 ± 3.6 | 12.6 ± 4.0a | −19 | 2.01 (1.21 to 3.35) | 0.65 (0.53 to 0.76) |
| CtTh (μm) | 626 ± 179 | 743 ± 241b | −16 | 1.78 (1.09 to 2.91) | 0.61 (0.49 to 0.73) |
| TbN (1/mm) | 1.7 ± 0.5 | 2.0 ± 0.4b | −12 | 1.79 (1.13 to 2.83) | 0.64 (0.52 to 0.77) |
| trabecular thickness (μm) | 59 ± 13 | 64 ± 13 | −8 | 1.62 (0.98 to 2.70) | 0.58 (0.45 to 0.71) |
| TbSp (μm) | 574 ± 206 | 477 ± 164b | 20 | 1.71 (1.07 to 2.74) | 0.65 (0.53 to 0.78) |
| TbSpSD (1/μm) | 315 ± 214 | 218 ± 146a | 44 | 1.76 (1.07 to 2.91) | 0.65 (0.53 to 0.78) |
| HRpQCT, tibia | |||||
| total area (mm2) | 769 ± 139 | 771 ± 147 | −0.3 | 1.02 (0.66 to 1.57) | 0.50 (0.37 to 0.63) |
| CtArea (mm2) | 90 ± 46 | 110 ± 38b | −18 | 1.73 (1.04 to 2.88) | 0.67 (0.55 to 0.79) |
| trabecular area (mm2) | 679 ± 133 | 662 ± 143 | 3 | 0.88 (0.57 to 1.36) | 0.55 (0.42 to 0.67) |
| Dtot (mg HA/cm3) | 226 ± 56 | 259 ± 63b | −13 | 1.85 (1.11 to 3.09) | 0.65 (0.53 to 0.76) |
| Dcort (mg HA/cm3) | 744 ± 87 | 786 ± 77b | −5 | 1.70 (1.07 to 2.68) | 0.62 (0.50 to 0.74) |
| Dtrab (mg HA/cm3) | 142 ± 37 | 158 ± 48 | −10 | 1.48 (0.92 to 2.37) | 0.57 (0.45 to 0.70) |
| BV/TV (%) | 11.8 ± 3.1 | 13.2 ± 4.0 | −10 | 1.48 (0.92 to 2.38) | 0.58 (0.45 to 0.70) |
| CtTh (μm) | 793 ± 374 | 979 ± 338b | −19 | 1.82 (1.09 to 3.02) | 0.68 (0.56 to 0.80) |
| TbN (1/mm) | 1.7 ± 0.4 | 1.9 ± 0.5 | −8 | 1.44 (0.92 to 2.25) | 0.58 (0.46 to 0.70) |
| trabecular thickness (μm) | 68 ± 12 | 69 ± 10 | −2 | 1.11 (0.71 to 1.72) | 0.56 (0.43 to 0.68) |
| TbSp (μm) | 542 ± 189 | 494 ± 179 | 10 | 1.29 (0.84 to 1.98) | 0.58 (0.46 to 0.70) |
| TbSpSD (1/μm) | 292 ± 232 | 248 ± 163 | 18 | 1.25 (0.82 to 1.92) | 0.56 (0.44 to 0.68) |
aP < 0.01.
bP < 0.05.
cP < 0.001.