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MC1R agonist treatment reduces oxidative stress in PHN rats. Urine samples were collected after 4 weeks of treatment. TBARS were measured and related to the creatinine concentration. TBARS were significantly decreased in MS05-treated PHN rats (T, n = 8) compared with untreated PHN (U, n = 6). Data are presented as mean ± SEM, *P < 0.05.
