Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
TLR4 deficiency reduces MMP9 but not MMP2 activity after UUO. (A and B) Quantification of latent and active MMP2 (A) and MMP9 (B) in obstructed kidneys of WT (□) and TLR4−/− (■) mice after UUO. No differences are observed in the renal levels of latent or active MMP2 between WT and TLR4−/− mice. The levels of latent and active MMP9 are significantly lower in the kidneys of TLR4−/− mice 14 days after UUO. Data are means ± SEM of seven mice per group. *P < 0.05.
