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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: J Gene Med. 2010 Aug;12(8):681–692. doi: 10.1002/jgm.1486

Figure 7. In vivo imaging of the spread of oncolytic adenovirus in malignant mesothelioma xenograft tumors.

Figure 7

MESO4 tumors were grown subcutaneously in nude mice to approximately 5–6 mm in diameter, and injected intratumorally with 5 × 108 TU of either Ad881 or Ad884, or PBS control on Day 0 (n = 3 per group). At different time points indicated in the figure, whole body images (0.05- to 0.5-second exposure) were taken and analyzed by in vivo fluorescence imaging. Representative images are shown from each group.