Fig. 3.

Correlation and effect sizes of TF binding and gene expression. (A) Example showing a correlation of binding and expression. This figure also shows a transgression event, in which the daughter displays a strong increase in binding relative to the parents. Continuous signal tracks shown in Fig. S10C. (B) Regions with binding variation correlate with differences in expression. Dark blue dots: PolII BRs displaying significant differences in binding in pair-wise comparisons between individuals; light blue dots: other BRs. The black lines demarcate data points that either fall two standard deviations outside the binding ratio or gene expression distributions. Indicated counts represent data points falling into the four corners for each data set. (C) Strong correlation between binding and gene expression at BRs in which a B-SNP intersects with the PolII specific CAAT-box. (D) Breakdown of segregation events in the trio showing the extent of BRs with candidate transgression events.