Table 1.
Patient Characteristics at Diagnosis
| Treatment Received | p value | |||
|---|---|---|---|---|
| No Corticosteroid (n=8) |
Corticosteroid (n=30) |
|||
| Sex (#, %) | 6 F (75) | 22 F (73) | 1.0 | |
|
Ethnicity (#, %) |
Caucasian | 6 (75) | 14 (47) | 0.90 |
| Black | 1 (12.5) | 7 (23) | ||
| Asian | 0 | 1 (3) | ||
| Hispanic | 1 (12.5) | 6 (20) | ||
| Other | 0 | 2 (7) | ||
|
Age (median years, range) |
8.0 (4.3 – 12.3) | 7.9 (1.9 – 17.4) | 0.9 | |
|
Duration of Symptoms (median weeks, range) |
8 (4 – 52) | 8 (2 – 52) | 0.75 | |
|
Muscle Enzymes (median, range) (U/l) |
CPK (N<238) |
177 (69 – 2932) | 1022 (32 – 83440) | 0.42 |
|
aldolase (N<7.0) |
10.5 (6.7 – 26) | 15.8 (6.5 – 106.9) (n=20) |
0.14 | |
|
AST (N<38) |
35 (23 – 217) | 83 (16 – 1110) (n=24) |
0.47 | |
|
ALT (N<41) |
27 (11 – 220) | 59 (14 – 540) (n=24) |
0.33 | |
|
LDH (N<221) |
290 (240 – 415) (n=4) |
438 (180 – 3741) (n=23) |
0.34 | |
|
vWF Ag (median, range) (N 50 – 150%) |
100 (22 – 166) (n=6) |
184 (52 – 420) (n=20) |
0.03 | |
CPK = creatine phosphokinase, AST = aspartate aminotransferase, ALT = alanine aminotransferase, LDH = lactate dehydrogenase, vWF Ag= von Willebrand factor antigen. For comparison of laboratory test values, number of subjects with test results available for each group is noted if different than total number in group.