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Effect of sodium nitroprusside (SNP, 1 µM), NS309 (1 µM) and CyPPA (6 µM) on bradykinin relaxation (A). Effect of NS309 (1 µM) and CyPPA (6 µM) on SNP relaxation (B). Effect of NS309 (1 µM) on bradykinin relaxation in the absence and presence of apamin (0.5 µM), and/or charybdotoxin (ChTx, 0.1 µM) (C). Effect of CyPPA (6 µM) on bradykinin relaxation in the absence and presence of apamin (0.5 µM) (D). Results are mean ± SEM (n = 6–8). Two-way anova. *P < 0.05 from control.
