Table 3.
Results from stratified meta-analyses of age, sex, and body size adjusted hazard ratios of associations of walking speed and chair rise time with all cause mortality: lowest versus highest quarter comparison
| Stratification | Walking speed | Chair rise time | |||||||
|---|---|---|---|---|---|---|---|---|---|
| No* | Summary hazard ratio (95% CI) | I2 (%) | P value† | No* | Summary hazard ratio (95% CI) | I2 (%) | P value† | ||
| None | 5 | 2.87 (2.22 to 3.72) | 25.2 | 0.25 | 5 | 1.96 (1.56 to 2.46) | 81.9 | <0.01 | |
| Mean age at baseline (years): | |||||||||
| ≤60 | 0 | – | – | – | 0 | – | |||
| 61-70 | 1 | 6.25 (2.79 to 14.02) | – | – | 0 | – | 81.9 | <0.01 | |
| >70 | 4 | 2.68 (2.14 to 3.35) | 0 | 0.71 | 5 | 1.96 (1.56 to 2.46) | |||
| Length of follow-up (years): | |||||||||
| ≤5 | 4 | 3.11 (2.37 to 4.09) | 13.3 | 0.33 | 1 | 1.90 (1.26 to 2.87) | – | – | |
| 6-10 | 1 | 2.16 (1.38 to 3.38) | – | – | 3 | 2.14 (1.86 to 2.48) | 8.7 | 0.34 | |
| 11-20 | 0 | – | – | – | 1 | 1.50 (1.38 to 1.63) | – | – | |
| >20 | 0 | – | – | – | 0 | – | – | – | |
| Region of study: | |||||||||
| North America | 2 | 3.95 (1.89 to 8.28) | 61.9 | 0.11 | 3 | 1.85 (1.42 to 2.41) | 88.0 | <0.01 | |
| Japan | 0 | – | – | – | 0 | – | – | – | |
| Other | 3 | 2.61 (2.02 to 3.37) | 0 | 0.54 | 2 | 2.26 (1.58 to 3.23) | 27.7 | 0.24 | |
| Sex‡: | |||||||||
| Male | 4 | 2.65 (2.01 to 3.48) | 0 | 0.58 | 3 | 2.17 (1.82 to 2.58) | 17.3 | 0.30 | |
| Female | 4 | 3.19 (2.20 to 4.63) | 6.7 | 0.36 | 3 | 1.77 (1.36 to 2.30) | 67.0 | 0.05 | |
*Number of data points.
†From Cochran’s Q statistic.
‡Total numbers differ for sex stratified meta-analyses for following reasons: walking speed quarter comparison estimates include one study of men only and one study of women only (unstratified summary hazard ratio for comparison 2.83 (2.28 to 3.51), n=8, I2=0%, P=0.56); chair rise time quarter comparison estimates include two studies of men only and two studies of women only (unstratified summary hazard ratio for comparison 2.00 (1.62 to 2.46), n=6, I2=78.1%, P<0.01).