Fig. 6.
Histological images following infusate CED into the dorsal hippocampus showing Evans blue dye spreading throughout the dorsal hippocampus. (A, C) Fluorescence images of 2 subjects showing limited penetration in the dorsal hippocampal dense granule cell layer (filled arrowhead) and pyramidal cell layer (unfilled arrowhead). Preferential distribution can be seen in the hippocampal fissure (asterisks) and alveus (filled arrow). (B) Black-gold stained image in close proximity to (A) confirming alveus and dense cell layer approximations. (D) Cresyl violet staining of a section in close proximity to (C) confirming dense cell layers.