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. Author manuscript; available in PMC: 2010 Sep 14.
Published in final edited form as: Eur J Immunol. 2009 May;39(5):1313–1322. doi: 10.1002/eji.200838916

Figure 1. 6.9 TCR-Tg TGF-β-induced Tregs suppress diabetes transfer by diabetic NOD spleen cells and also spontaneous diabetes in 2.5 TCR-Tg/NOD.scid recipients.

Figure 1

A. NOD diabetic spleen cells (SC) (1 × 107) were injected into NOD.scid mice ≤ 2 weeks of age either alone or co-injected with TGF-β-induced Tregs (1 × 107) from either 6.9 TCR-Tg/NOD.C6 mice or 2.5 TCR-Tg/NOD mice. B. 2.5 TCR-Tg/NOD.scid mice were injected at ≤ 18 days of age with 6.9 TCR-Tg TGF-β-induced Tregs (1 × 107). Diabetes incidence was measured by daily urine glucose readings, and positive readings were confirmed by blood glucose analysis.