Representative PET co-registered to MR images showing the distribution of radioactivity in human brains after the administration of [11C]-verapamil before (B,E) and during (C,F) cyclosporine infusion (2.5 mg/kg/hr). The MR images are shown in the left panel. C, caudate nucleus; Cb, cerebellum; FC, frontal cortex; OC, occipital cortex; Pu, putamen; Pi, pituitary; T, thalamus, V, lateral ventricle. Images B and C, and E and F were scaled to the same pixel value.