Table 1.

Drugs associated with erectile dysfunction

TYPE OF DRUG	EXAMPLES
Acid suppression	ranitidine, cimetidine
Anticonvulsants	carbamazepine, gabapentin, phenytoin, phenobarbital, pregabalin,11 topiramate
Antidepressants	SSRIs, TCAs, lithium, MAOIs
Antipsychotics	haloperidol, phenothiazines
Antihypertensives	BBs, methyldopa, clonidine; CCBs (less likely)
Cardiac-related	digoxin, fibrates, statins
Diuretics	spironolactone, thiazides (especially higher doses than are now used for hypertension, eg, hydrochlorothiazide ≥ 50 mg)
Hormonal	progesterone, estrogen, corticosteroids, 5α-reductase inhibitors, cyproterone acetate
Immunomodulators	interferon α
NSAIDs	indomethacin12

BB—β-blocker, CCB—calcium channel blocker, MAOI—monoamine oxidase inhibitor, NSAID—nonsteroidal anti-inflammatory drug, SSRI—selective serotonin reuptake inhibitor, TCA—tricyclic antidepressant. Data from Katz and Katz,⁹ McVary,¹⁰ Hitiris et al,¹¹ and Miller et al.¹²