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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: J Nutr Biochem. 2010 Nov;21(11):1015–1032. doi: 10.1016/j.jnutbio.2010.01.005

Table 4. Potential factors contributing to observation of somewhat different obese phenotype noted with “L-FABP null/GFP overexpressor” mice.

Differences were derived by comparisons of methodology reported for “L-FABP null/GFP overexpressor mice” [143, 163-165, 182, 197] with those for the original “L-FABP null mice” mice [45, 56, 59, 71, 98, 142, 152, 153, 162, 167, 176, 177]. Additional references in the table refer to other publications demonstrating such differences in factors/parameters can affect mouse phenotype/obesity/lipid metabolism.

Factor Parameter Affects Mouse Phenotype/Lipid Metabolism/Obesity Additional References
Construct Lipid phenotype Yes [198-200]
Peptide fragments? Yes [201-208, 208, 209, 209-215]
GFP overexpression Yes [216-221]
Backcrossing C57BL/J substrain more obesity susceptible Yes [222], http://jaxmice.jax.org/jaxnotes/511/511n.html
Backcross generation number of L-FABP null No [98]
Control mice Vendor supplied vs wild-type littermates Yes
Age Yes [223-225]
Sex Yes [58, 169]
Diets Vendor source, non-defined, not phytol free, not phytoestrogen free Yes [58, 168, 171, 172]
Ad libitum feeding, length of time on high fat diet Yes
Intestinal microflora Obesity Yes [226-231]