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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: Prog Neuropsychopharmacol Biol Psychiatry. 2010 Jul 17;34(7):1279–1284. doi: 10.1016/j.pnpbp.2010.07.008

Table 2.

Escitalopram doses and treatment outcomes.

Medication Range Mean
Escitalopram (mg/day) 5–20 12.5 ± 5.08*
Measures Baseline 2 week 4 week 6 week 8 week 12 week F1 d.f.2 p1
BDNF levels (ng/ml) 16.90 ± 3.91* NA 16.32 ± 3.17* NA 17.08 ± 3.85* 14.93 ± 3.68* 2.27 1, 45.5 0.138
CAPS scores 61.81 ± 14.62* NA NA NA NA 28.86 ± 17.91* 38.61 1, 14.8 < 0.001
PCL scores 56.00 ± 11.96* 44.81 ± 13.05* 41.56 ± 12.06* 37.50 ± 11.45* 35.87 ± 11.69* 31.47 ± 13.26* 70.50 1, 78.1 < 0.001
HAM-D scores 18.19 ± 7.29* NA NA NA NA 6.13 ± 4.61* 57.64 1, 14.6 < 0.001
*

Values are given as mean ± standard deviation.

CAPS: Clinician Administered PTSD Scale; PCL: PTSD Checklist; HAM-D: Hamilton Depression scale; NA: Not Available.

1

Linear change over time based on mixed model analysis of all available time points.

2

Denominator degrees of freedom are Satterthwaite estimates from the mixed model, and need not be integer values.