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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: Gynecol Oncol. 2010 Jul 31;119(1):140–145. doi: 10.1016/j.ygyno.2010.06.024

Figure 3. IC50s of Patupilone and Paclitaxel in six USPC cell lines.

Figure 3

Symbols (error bars) denote means (standard deviations) of IC50s. Text to the left of the symbols denotes the cell line, its paclitaxel/patupilone ratio of IC50s, and the ratio’s P value. Note that the individual ratios are significant (at P<0.05) for the cell lines that show HER-2/neu amplification by FISH, but not significant in the cell lines that don’t. As a class, the three HER-2/neuamplified lines taken together showed significantly lower IC50s for patupilone compared to paclitaxel (P=0.0002), whereas the three unamplified lines taken together did not (P=0.54).