Skip to main content
. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: Schizophr Res. 2010 Aug 11;123(1):15–21. doi: 10.1016/j.schres.2010.06.015

Table 3.

Absolute and relative regional prefrontal gray matter volumes in familial high-risk (FHR) and control youth

Absolute Volumesa Relative Volumesb
FHR
n = 27
Controls
n = 48
FHR
n = 27
Controls
n = 48
%
Difference c
de
Ventromedial, total 4.53 ± 0.18 4.89 ± 0.12 0.38 ± .01 0.42 ± .01 d −9.22 −0.57
Frontal Pole, total 67.19 ± 2.25 71.07 ± 1.65 5.72 ± .17 6.14 ± .12 d −6.90 −0.50
Dorsolateral, total 58.75 ± 2.23 59.17 ± 1.15 4.96 ± .13 5.12 ± .09 −3.07 −0.25
Ventrolateral, total 16.93 ± 0.51 16.18 ± 0.40 1.44 ± 0.04 1.40 ± 0.03 3.22 0.23
Orbitofrontal, total 13.50 ± 0.54 12.57 ± 0.36 1.15 ± 0.04 1.09 ± 0.03 5.52 0.27
a

Absolute volumes in cubic centimeters are given as mean ± standard error;

b

Significant group × region interaction (p ≤ .04) in the repeated measures multivariate analysis of covariance predicting left and right relative prefrontal volumes in FHR vs. control subjects, adjusting for total cerebral volume and age;

c

Percent differences calculated from volumes using five decimal points for accuracy;

d

Significant difference between groups in follow-up least square mean contrasts, p ≤ .05;

e

effect size reported as Cohen’s d.

HHS Vulnerability Disclosure