TABLE 1.
Pre-operative clinical, postoperative pathological, and follow-up characteristics of men undergoing radical prostatectomy in the SEARCH Database who were potential active surveillance candidates
| No. patients | 347 |
| Mean age ± SD (yr) | 60.3 ± 6.5 |
| Median year of surgery (IQR) | 2001 (1998, 2003) |
| No. Race (%) | |
| Non-black | 202 (58) |
| Black | 145 (42) |
| No. body mass index (%) | |
| Normal weight | 90 (28) |
| Overweight | 126 (39) |
| Obese | 107 (33) |
| No. Agent Orange Exposure (%) | 58 (19) |
| PSA (ng/ml) | |
| Mean ± SD | 5.7 ± 2.2 |
| Median | 5.5 |
| No. biopsy Gleason score (%) | |
| 4 | 19 (5) |
| 5 | 33 (10) |
| 6 | 295 (85) |
| No. clinical stage (%) | |
| T1a | 4 (1) |
| T1c | 251 (72) |
| T2a | 92 (27) |
| Median biopsy cores obtained (IQR) | 8 (6, 10) |
| No. cores positive (%) | |
| 1 | 227 (65) |
| 2 | 120 (35) |
| No. pathological Gleason score (%) | |
| 2–6 | 220 (64) |
| 3+4 | 97 (28) |
| ≥4+3 | 29 (8) |
| No. positive surgical margins (%) | 122 (35) |
| No. extracapsular extension (%) | 56 (16) |
| No. seminal vesicle invasion (%) | 7 (2) |
| No. positive lymph nodes (%) | 0 (0) |
| No. lymph adenectomy not performed (%) | 120 (35) |
| Follow-up length (months) | |
| Mean ± SD | 58 ± 38 |
| Median | 54 |
| No. recurrences (%) | 55 (16) |
| Median PSA doubling time at recurrence* (mo) | 20.2 |
*
data only available on 27 of the 56 men with recurrence