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Average R.Q. ratio of DA D1 and DA D2 receptors, and TH (Panel A); NMDAR1 and NMDAR2A (Panel B) for WT and NTS1−/− mice following chronic PCP administration relative to saline treated mice. Mouse brains were harvested, dissected on ice, and frozen at −80°C until assayed. Brain tissue was homogenized and assayed as described in Materials and Methods. Results are presented as mean ± S.E.M (N=5~7 for each group). P<0.05 is considered significant. *, P<0.05.
