Skip to main content
. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: Neurobiol Dis. 2010 Jul 24;40(2):467–477. doi: 10.1016/j.nbd.2010.07.011

Table 2.

Qualitative summary of the experimental results.

Baseline Acute PCP study Chronic PCP study
WT NTS1 −/− AP-WT AP-NTS1−/− CP-WT CP-NTS1−/−
Behavioral tests Locomotor activity graphic file with name nihms225912ig1.jpg +++ +++ graphic file with name nihms225912ig1.jpg ++ ++
FST graphic file with name nihms225912ig1.jpg +++ N/A N/A +++ +++
TST graphic file with name nihms225912ig1.jpg +++ N/A N/A +++ +++
Microdialysis DA graphic file with name nihms225912ig1.jpg graphic file with name nihms225912ig1.jpg +++ graphic file with name nihms225912ig1.jpg graphic file with name nihms225912ig1.jpg − − −
Glu graphic file with name nihms225912ig1.jpg − − − +++ graphic file with name nihms225912ig1.jpg − − − −
mRNA DA D1 graphic file with name nihms225912ig1.jpg − − − N/A N/A − − − − −
DA D2 graphic file with name nihms225912ig1.jpg − − − N/A N/A − − − − − −
TH graphic file with name nihms225912ig1.jpg graphic file with name nihms225912ig1.jpg N/A N/A graphic file with name nihms225912ig1.jpg graphic file with name nihms225912ig1.jpg
NMDAR1 graphic file with name nihms225912ig1.jpg graphic file with name nihms225912ig1.jpg N/A N/A ++ graphic file with name nihms225912ig1.jpg
NMDAR2A graphic file with name nihms225912ig1.jpg − − − N/A N/A − − − − − −
Binding assay DA D2 graphic file with name nihms225912ig1.jpg − − − N/A N/A − − − − − −
NMDAR2A graphic file with name nihms225912ig1.jpg − − − N/A N/A − − − − − −

“Grayed-out areas” = No change as compared with WT baseline

“+++” = large increase

“++” = moderate increase

“−−−” = large decrease

“−−” = moderate decrease N/A= not tested