Table 1.

Human TREX proteins

Antibodies against THOC2, UAP56, and CIP29 were used to immunopurify the TREX complex from HeLa nuclear extracts. Mass spectrometry was carried out on the total proteins. Protein aliases, calculated molecular weights (in kilodaltons), and UniProt accession numbers are shown. The number of total (T) and unique (U) peptides is shown.

^aDDX39 (90% identical, 96% similar to UAP56) was detected in all three IPs with four, six, and three unique peptides for THOC2, UAP56, and CIP29, respectively. Peptides unique to UAP56 were also present in all three IPs with 11, 18, and 15 for THOC2, UAP56, and CIP29, respectively.

The table shows all of the unique peptides for DDX39 and UAP56, plus the unique peptides common to both proteins (19, 11, and 23, respectively for the three IPs).