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Proposed mechanism of Aβ peptide and N-ter Tau fragment interaction with mitochondria; for further details see text. mom, mitochondrial outer membrane; mim, mitochondrial inner membrane; TOM, translocase of the outer membrane; I–V, respiratory chain complexes; cyt c, cytochrome c; ANT, adenine nucleotide translocator; CyD, cyclophilin D; mPTP, mitochondrial permeability transition pore.
