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. 2010 Sep;38(9):1582–1588. doi: 10.1124/dmd.110.032961

TABLE 1.

EC50 and 95% CI for parathion compared with other mCAR activators

Chemical EC50 a 95% CI a Agonist b
μM
Parathion 1.426 0.481–4.233 Full
Chlorpyrifos 1.288 0.809–2.049 Full
Nonylphenol 2.386 1.357–4.195 Partial
TCPOBOP 0.0248 0.0147–0.040 Full

CI, confidence interval.

a

EC50 values and 95% CI were determined using GraphPad Prism 4.0 as described under Materials and Methods.

b

Chemicals that show reduced efficacy compared with TCPOBOP are considered partial agonists.