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. 2010 Sep;78(3):511–523. doi: 10.1124/mol.110.064493

Fig. 7.

Fig. 7.

The influence of PD81,723 and VUF5455 on the binding and function of 30 nM ABA-X-BY630 at the human adenosine A3 receptor. a, the association and dissociation kinetics of 30 nM ABA-X-BY630 in the absence (●; n = 14) and presence of 1 (○; n = 9) and 10 μM (closed gray circle; n = 6) PD81,723 at CHO-A3 cells. b, the intracellular calcium mobilization mediated by 30 nM ABA-X-BY630 in the absence (●; n = 14) and presence of 1 (○; n = 9) and 10 μM (closed gray circle; n = 6) PD81,723 at CHO-A3 cells. c, normalized association kinetics of 30 nM ABA-X-BY630 in the absence (●; n = 14) and presence of 1 (○; n = 9) and 10 μM (closed gray circle; n = 6) PD81,723 at CHO-A3 cells. d, normalized dissociation kinetics of 30 nM ABA-X-BY630 in the absence (●; n = 14) and presence of 1 (○; n = 9) and 10 μM (closed gray circle; n = 6) PD81,723 at CHO-A3 cells. e, the association and dissociation kinetics of 30 nM ABA-X-BY630 in the absence (●; n = 14) and presence of 0.1 (○; n = 7) and 1 μM (closed gray circle; n = 6) VUF5455 at CHO-A3 cells. f, the intracellular calcium mobilization mediated by 30 nM ABA-X-BY630 in the absence (●; n = 14) and presence of 0.1 (○; n = 7) and 1 μM (closed gray circle; n = 6) VUF5455 at CHO-A3 cells. g, normalized association kinetics of 30 nM ABA-X-BY630 in the absence (●; n = 14) and presence of 0.1 (○; n = 7) and 1 μM (closed gray circle; n = 6) VUF5455 at CHO-A3 cells. h, normalized dissociation kinetics of 30 nM ABA-X-BY630 in the absence (●; n = 14) and presence of 0.1 (○; n = 7) and 1 μM (closed gray circle; n = 6) VUF5455 at CHO-A3 cells.