Fig. 7.

Resveratrol inhibited LPS-induced MAPKs activation in microglia. Primary microglia-enriched cultures were pretreated with resveratrol (60 μM) for 30 min followed by LPS (10 ng/ml) treatment for 15 min. The whole-cell protein was harvested to perform Western blotting assay (A). The ratio of densitometry values of phosphorylated MAPKs compared with total MAPKs was analyzed and normalized to each respective control group (B). Results are the mean ± S.E.M. from three independent experiments. #, p < 0.05 compared with control cultures; *, p < 0.05 compared with LPS-treated cultures.