Table 2.

SLC2A10 sequence variants and association with PAD in type 2 diabetic patients at baseline.

#	ID	Position (kb)	Function	Major/ minor allele	Minor allele frequency PAD(-) PAD(+)		Allelic p-value (adjusted*)	Allele OR* (95% CI)	Genotype distribution** PAD (-) PAD (+)		Genotypic p-value (adjusted*)
1	rs2425895	-1.789	5' upstream	G/A	0.067	0.056	0.75 (0.83)	0.87 (0.24-3.13)	301:42:2	24:3:0	1.00 (0.82)
2	(TGTGTGTGT)n	-0.208	5' upstream	3/2	0.24	0.28	0.54 (0.38)	1.37 (0.68-2.80)	198:128:18	14:11:2	0.72 (0.39)
3	rs2143044	10.341	Intron 1	C/T	0.31	0.44	0.03 (0.03)	2.00 (1.04-3.85)	167:141:35	7:16:4	0.05 (0.04)
4	rs3092412	11.720	Intron 1	A/T	0.39	0.56	0.01 (0.005)	2.51 (1.31-4.81)	130:164:51	4:16:7	0.03 (0.006)
5	rs2235491	15.915	Exon 2 Ala206Thr	G/A	0.074	0.13	0.14 (0.036)	3.03 (1.08-8.55)	296:47:2	21:5:1	0.11 (0.05)
6	rs2425904	18.500	Intron 3	T/C	0.37	0.56	0.007 (0.004)	2.58 (1.34-4.98)	133:167:45	3:18:6	0.006 (0.004)
7	rs2425911	21.843	Intron 4	G/C	0.38	0.56	0.01 (0.005)	2.54 (1.32-4.87)	132:164:49	3:8:6	0.009 (0.005)
8	rs3091904	23.079	Intron 4	C/T	0.38	0.57	0.004 (0.002)	2.83 (1.46-5.46)	136:158:51	3:17:7	0.005 (0.002)
9	rs1059217	26.273	3' UTR	C/T	0.37	0.56	0.007 (0.004)	2.58 (1.35-4.95)	185:160:0	9:18:0	0.005 (0.004)
10	rs6066059	29.778	3' downstream	C/T	0.37	0.56	0.005 (0.004)	2.61 (1.36-5.00)	138:161:46	3:18:6	0.004 (0.004)
11	rs2179357	32.708	3' downstream	C/T	0.33	0.57	2.6 × 10-4 (< 0.0001)	3.87 (1.97-7.58)	160:143:42	4:15:8	0.001 (< 0.0001)

*P-values and odds ratios were adjusted for covariates including age, sex, duration of diabetes, BMI, triglyceride, total cholesterol, HbA1c, systolic blood pressure and current smoking status.

**Genotype distribution are shown as number (AA: AB: BB); A represents the major allele and B represents the minor allele.

PAD, peripheral artery disease; OR, odds ratio; CI, confidence interval