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. 2010 Aug 31;10:39. doi: 10.1186/1471-2261-10-39

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Copyright ©2010 Fosgerau et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Blood temperature (A) and respiration rate (B) in healthy conscious rats. Following baseline characterization animals were infused at t = 0 with vehicle control for 1 hour followed by incremental doses of DHC of 1.0; 2.0; 2.2; 2.4; and 3.0 mg/kg/hr for 1 hour at each condition. Statistics: Each of the doses of DHC were compared to the vehicle control situation by a 1-way ANOVA followed by Dunnett's multiple comparison test ***p > 0.001, **p < 0.01, *p < 0.05. Values are expressed as average ± SE, with n = 6, see Methods for further details.