Table 3.
Summary of the influence of VEGF SNPs on cancer OS
| First author | Year | Cancer | Country | Ethnicity | SNPs | No. | Risk allele |
|---|---|---|---|---|---|---|---|
| Guan (Current) | 2010 | LA-NSCLC | USA | Caucasian | -460T > C, -634G > C, and 936C > T | 124 | T for -460T > C |
| Formento [23] | 2009 | Head&neck | France | Caucasian | -460T > C, -634G > C, and 936C > T | 49 | None |
| Masago [20] | 2009 | Advanced NSCLC | Japan | Asian | -460T > C, -1154G > A, -2578C > A, 405G > C, and 936C > T | 126 | C for -460T > C, A for -1154G > A, and A for -2578C > A |
| Dassoulas [24] | 2009 | Colorectum | Greece | Caucasian | -460T > C, -634G > C, -1154G > A, -2578C > A, and 936C > T | 312 | T for -460T > C, G for -634G > C, C for -2578C > A, and C for 936C > T |
| Bradbury [25] | 2009 | Esophagus | Canada | Caucasian | -460T > C, 405G > C, and 936C > T | 361 | C for 936C > T |
| Heist [9] | 2008 | Early NSCLC | USA | Caucasian | -460T > C, 405G > C, and 936C > T | 462 | G for 405G > C and C for 936C > T |
| Kim [16] | 2008 | Colorectum | Korea | Asian | -634G > C, -2578C > A, and 936C > T | 445 | G for -634G > C and T for 936C > T |
| Kim [26] | 2007 | Stomach | Korea | Asian | -116G > A, -460T > C, 405G > C, and 936C > T | 503 | C for -460T > C and T for 936C > T |
| Kawai [27] | 2007 | Renal cell | Japan | Asian | -634G > C, -2578C > A, and -1154G > A | 213 | C for -2578C > A |
| Hefler [17] | 2007 | Ovarian | Austria | Caucasian | -634G > C, -1154G > A, and -2578C > A | 563 | None |
| Tzanakis [28] | 2006 | Stomach | Greece | Caucasian | -634G > C, -2578C > A, -1154G > A, and 936C > T | 100 | C for -634G > C |
| Lu [19] | 2005 | Breast | China | Asian | -460T > C, 405G > C, and 936C > T | 1119 | C for -460T > C, and G for 405G > C |