Table 1.

Pearson's correlation between optimal growth temperature (OGT) and amino acid usage before (R) and after (R_Comp) controlling for phylogenetic independence.

	Naïve analysis		Comparative method
Amino acid	R	p	RComp	p
A	-0.29	0.0021	0.051	0.49
C	-0.056	0.56	-0.27	0.00014
D	-0.27	0.005	-0.40	1.1E-08
E	0.49	4.6E-08	0.092	0.21
F	0.15	0.11	0.0089	0.90
G	-0.086	0.38	0.086	0.24
H	-0.39	3.5E-05	-0.069	0.34
I	0.25	0.0076	-0.084	0.24
K	0.30	0.0013	-0.025	0.72
L	-0.057	0.55	0.096	0.19
M	-0.10	0.29	-0.37	2.1E-07
N	0.033	0.73	-0.29	5.6E-05
P	-0.13	0.19	0.25	0.00049
Q	-0.43	3.3E-06	-0.35	9.5E-07
R	-0.051	0.59	0.27	0.00016
S	-0.10	0.27	-0.40	1.1E-08
T	-0.40	1.4E-05	-0.42	2.6E-09
V	0.17	0.083	0.11	0.14
W	-0.27	0.0030	-0.018	0.80
Y	0.40	1.8E-05	0.081	0.27