Table 3.
Estimated coefficients with p-values of PCBs and their subsets in relation to BISD at age of16 months, 2002-2004†.
| Log transformed | Maternal sera (N = 760) | Cord sera (N = 258) | ||||||
|---|---|---|---|---|---|---|---|---|
| Exposure Variables | MDI | PDI | MDI | PDI | ||||
| β | SE | β | SE | β | SE | β | SE | |
| 4 major PCBs‡ (∑non-dioxin-like PCBs) | -0.39 | 0.62 | -0.59 | 0.73 | -1.02 | 0.94 | -1.95* | 1.13 |
| ∑ Dioxin-like mono-ortho PCBs ‡ | -1.60*** | 0.45 | -1.26** | 0.53 | -1.40* | 0.72 | -1.99** | 0.87 |
| ∑Anti-estrogenic PCBs‡ | -0.47 | 0.61 | -0.58 | 0.72 | -0.93 | 0.94 | -1.85 | 1.13 |
| PCB 118 | -1.17*** | 0.39 | -1.04** | 0.46 | -1.44** | 0.64 | -2.04*** | 0.77 |
| PCB 138 | -0.30 | 0.59 | -0.53 | 0.70 | -1.35 | 0.91 | -2.27** | 1.09 |
| PCB 153 | -0.33 | 0.62 | -0.63 | 0.73 | -1.22 | 0.94 | -2.14* | 1.14 |
| PCB 156 | -1.46*** | 0.43 | -1.02** | 0.50 | -0.50 | 0.71 | -0.63 | 0.86 |
| PCB 170 | -0.54 | 0.60 | -0.58 | 0.71 | -0.62 | 0.77 | -1.90* | 0.94 |
| PCB 180 | -0.36 | 0.61 | -0.47 | 0.72 | -0.55 | 0.94 | -1.26 | 1.13 |
*P < 0.1; **P < 0.05; *** P < 0.01; Regression parameter coefficients represent score change in PDI and MDI for a one-unit change in loge [exposure concentration ng/mg lipid].
‡ ∑4 major PCBs (non-dioxin-like PCBs), sum of PCB #138, #153, #170 and #180; ∑ Dioxin-like mono-ortho PCBs, sum of PCB #118, and #156; ∑Anti-estrogenic PCBs, sum of PCB #138, #156, #170, and #180
† After adjusting for district, HOME, sex, Raven score from multiple linear regression models.