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. 2010 Aug 23;8:21. doi: 10.1186/1477-3155-8-21

Figure 1.

Figure 1

Generation of aptamer-conjugated AuNPs via in situ conjugation. (A) Schematic illustration of in situ conjugation of AuNPs with aptamers during laser ablation in an aqueous aptamer solution. (B) Spacer design and resulting mixed monolayer conjugated nanoparticles. Mixed monolayer formation and careful spacer design contribute to correct aptamer folding.